5 Best Weed Killers for Arizona – Reviews & Results

Are you searching for the best weed killer for Arizona and techniques to eliminate the weeds in your landscape? All of the modern controls from eliminating weeds to killing them, naturally as well organically are discussed in this guide made for residents living in Arizona.

Weeds found in Arizona state belong to invasive weed species that are far more difficult to control than common weeds. These tough weeds can only be controlled through the proper pre and post-emergent chemical sprays.

But choosing the right weed killer for Arizona can be hectic work without having the proper guidance. Spraying the wrong chemical could get the green foliage in the yard to dry. 

To ease you in choosing the best weed killer for Arizona, I built this guide to clarify the top weeds, killers, for weeds in Arizona. All aspects of weeds flora germination, classification, and control methods are well discussed in the guide.

Around The House
Ortho GroundClear Vegetation Killer Ready-To-Use with Comfort Wand, 1.33-Gallon
Best For Professionals
RM43 43-Percent Glyphosate Plus Weed Preventer Total Vegetation Control, 2.5-Gallon
Strongest Natural Killer
Calyptus 45% Pure Super Concentrated Vinegar | Dilutes to 9 Gallons | 9x Power Cleaning Vinegar |...
Ortho GroundClear Vegetation Killer Ready-To-Use with Comfort Wand, 1.33-Gallon
RM43 43-Percent Glyphosate Plus Weed Preventer Total Vegetation Control, 2.5-Gallon
Calyptus 45% Pure Super Concentrated Vinegar | Dilutes to 9 Gallons | 9x Power Cleaning Vinegar |...
Around The House
Ortho GroundClear Vegetation Killer Ready-To-Use with Comfort Wand, 1.33-Gallon
Ortho GroundClear Vegetation Killer Ready-To-Use with Comfort Wand, 1.33-Gallon
Best For Professionals
RM43 43-Percent Glyphosate Plus Weed Preventer Total Vegetation Control, 2.5-Gallon
RM43 43-Percent Glyphosate Plus Weed Preventer Total Vegetation Control, 2.5-Gallon
Strongest Natural Killer
Calyptus 45% Pure Super Concentrated Vinegar | Dilutes to 9 Gallons | 9x Power Cleaning Vinegar |...
Calyptus 45% Pure Super Concentrated Vinegar | Dilutes to 9 Gallons | 9x Power Cleaning Vinegar |...

Let’s get started.

Common Weeds in Arizona

Many types of weeds are found in the Arizona region. These weeds are commonly classified into two types.

Narrow leaf weeds (Unwanted grasses)

All of the narrow-leafed weeds and the unwanted grasses that grow other than their proper place are placed in this category. These grasses are commonly found in the grassy lawns of bermudagrass.

Bromegrass is considered a weed and invasive species that increase the risk of wildfires as it spreads quickly in the lawn and becomes uncontrolled. These weeds disturb the growth and habit of the intentionally grown grass.

The other common grass weeds are Foxtail and Orchard grass that controls your landscape rapidly. You should remove or control these weedy grasses immediately to flourish your landscape. 

Special herbicides are used to control such types of weed grasses, without damaging the actual plants in the lawn. 

Broadleaf Weeds

Broadleaf weeds are the second type of weeds found in landscapes. These weeds can easily be distinguished by their flat and broad leaves that are wider than the common grass leaves in the lawns. 

Being a weed plant, these broadleaf weeds grow more rapidly than common grasses as they consume more sunlight due to their wider leaves. In the presence of water and nutrients along with more sunlight, these broadleaf weeds grow rapidly in lawns.

The common broadleaf weeds found in Arizona state are goosefoot, pigweed, and purslane. All of these weeds have fast-spreading that takes over the control of the resources of growth before the desirable plants. 

The other broadleaf weeds are puncturevine and bur clover. They are the most difficult to control due to the pain and itching that is caused to humans and animals. 

what does Silver Nightshade weed look like?

Silver Nightshade is the other broadleaf weed that has a huge toxic effect on livestock. They cause health problems in animals if they get eaten by any livestock animal. 

The most problematic broadleaf weed is Tumbleweed that is easier to spot but difficult to control. Such weeds spread very rapidly and produce thousands of seeds that spread long miles through animals and humans. A special control strategy is needed to control Tumbleweed.

what does tumbleweed look like

Difference Between Pre- & Post-Emergent Weed Spraying

Weedicides and herbicides are majorly classified into two main types on the basis of the actual application time. These are classified by the mode of application i.e. actual weeds growth stage. 

The common types of weedicides are pre-emergent and post-emergent weedicides. 

Pre-Emergent Weed Sprays

Pre-Emergent weedicides are sprays that are applied before the emergence of weeds. These chemicals typically target the seed of weeds to create a barrier to their germination.

Pre-Emergent weedicides are actually used for controlling the annual weeds like crabgrass and goosegrass.

The pre-emergent weedicides are applied when the outdoor temperature is lowest, before the soil temperature warm-up. They only benefit if applied before the emergence of the actual plant.

Application process

Such pre-emergent herbicides and weedicides come in granular and spray form. You can either apply them by spraying or sprinkling granules on the soil surface. 

If going to apply the granules on the soil surface, watering will help the chemical to absorb in soil easily and rapidly.

Post-Emergent Weed Sprays

Post-Emergent weedicides are used for controlling the invasive bermudagrass that comes year after year. Weeds having extensive root systems are easily controlled by post-emergent sprays.

These chemicals are sprayed or sprinkled over the already emerged plants.

Application process

These weedicides and herbicides work by directly attacking the plant roots and poisoning their root system. Post-emergent weedicides come in both liquid and granules forms.

For using the liquid form, just make the solution of the chemical and spray it directly over the plant. 

In the case of granular chemicals, sprinkle the granules over the soil surface and water the plants fully.

These works by shriveling and yellowing the leaves and brown stalking in the weeds and unwanted plants.

Products: Best weed killer for Arizona

1. Roundup QuikPro, 6.8 lb. Jug

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QuickPro is a non-selective herbicide by Roundup that is the most suitable and best weed killer for Arizona weeds. Roundup is a famous brand for producing quality herbicides and weedicides. 

This herbicide has Glyphosate as the active ingredient that kills the green plants immediately after the spray by blocking the enzymatic action in the plant body.

The great thing about this herbicide is the addition of diquat dibromide that is a highly active agent for controlling the weeds and woody bushes. This chemical agent is actually used for professional-grade herbicides but the addition of diquat to this herbicide makes it a professional herbicide.

Furthermore, the addition of surfactant in the herbicide makes it more sticky to the plant’s body. 

This herbicide is widely used for controlling broadleaf and grass weeds. It also works great for killing the woody bushes, roots, and trees. 


  • Non selective herbicide
  • Glyphosate as active ingredient
  • Addition of diquat makes it more faster in killing
  • Surfactant is mixed by manufacturer for more sticking
  • Controls all type of broadleaf and grass weeds
  • Best weed killer for Arizona

2. Ortho GroundClear Vegetation Killer Concentrate

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Ortho GroundClear Vegetation killer is a fast-acting, nonselective herbicide that kills all the vegetation in less than 6 hours. It is a concentrated and highly active formula by Ortho for controlling weeds.

This nonselective herbicide is a top weed killer for Arizona for killing hard weeds and bushes. The active ingredients of these herbicides are glyphosate and imazapyr, both are highly active materials for killing vegetation.

All you need to do is cover the desirable plants with plastic sheets and spray over the weeds and you will see the results in 6 hours.

The great thing of this herbicide is the versatility of application i.e. three modes of application as ready to use Wand and Refill, ready to use Sprinkler Cap, and concentrates. 

In the first method, you need to attach the comfort wand, available with the product, and apply the concentrated chemical on spot. While in the second method, you need to attach the sprinkler cap to the bottle and sprinkle the concentrated chemical over the weeds. In the third method, you need the ortho dial and spray or sprayer for spraying over plants.

This fast-acting formula prevents the unwanted weeds from growing again for up to 1 year.


  • Prevents the regrowth of weeds for up to 1 year
  • Non selective herbicide
  • Imazapyr and Glyphosate active ingredients
  • Three modes of application
  • Gives result in 6 hours
  • Best weed killer for unwanted plants

3. Compare-N-Save Concentrate Grass and Weed Killer, 41-Percent Glyphosate

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Compare-N-Save concentrate grass and weed killer is a powerful and nonselective herbicide for killing the vast type of weeds in the Arizona region. It kills the weed from the leaves to the roots system and makes them gone for years.

It has a powerful active ingredient, Glyphosate, that kills almost all types of annual, perennial weeds, and grass weeds. The concentration of glyphosate is 41%, which is an impressive figure for the faster killing of hard bushes and weeds.

All you need is to mix the 1.5 ounces or 3 tablespoons of concentrate in 1 gallon of water and spray it over the weeds. In case of killing the tougher weeds like perennials, mix 5 tablespoons of concentrate in 1 gallon of water and spray it.

It will take 2-4 days to show the visible results.

The great thing about this herbicide is that it kills the plants to the roots, making it ungrowable for next year. This herbicide is widely used for killing unwanted growth along the walkways and driveways.


  • Powerful herbicide
  • Kills almost all annual and perennial weeds
  • 41% active ingredients
  • Glyphosate as active agent
  • Takes 2-4 days in results
  • Kills to the roots
  • Best weed killer for perennial weeds

4. Roundup 5705010 Extended Control Weed and Grass Killer Plus Weed Preventer Concentrate

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Roundup 5705910 is a double-action, extended, concentrated weed and grass weed killer that kills the existing weeds as well as prevents the upcoming weeds.

It is an advanced formula by Roundup to kill the unwanted plants from any foundations, patios, driveways, and sidewalks. People often used this concentrate for killing the vegetation growing in the gravel areas.

The premium feature of this herbicide is the extended prevention of weeds regrowth at that place for up to 4 months. 

All you need to do is simply adding the 6 fl. oz. of concentrate in 1 gallon of water and spray over the selected area. Make sure to save the desired plants from even a single drop of spray. 

It gives valuable results in 6 hours due to its fast-acting nature. The great thing along with the fast action is its rainproof nature in 30 minutes. 


  • Dual action formula
  • Extended weed control and prevent
  • Easy application
  • Rainproof in 30 minutes
  • Give results in 6 hours
  • Kills weeds to roots

5. Ortho Weed B Gon Weed Killer for Lawns Ready-To-Use2 with Comfort Wand

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Ortho weed B Gon weed killer is a specially formulated herbicide for killing the weeds in lawns. It is a selective herbicide that kills some selective types of broadleaf weeds and dandelions.

The premium feature of this herbicide is that it is safe for lawns and does not cause any harm to them. You can safely apply the solution over the grass and can also spot treatment.

For getting the best results from this selective herbicide, it is directed to apply over the weeds at any time. It will kill the weeds to the roots and prevent their regrowth from the roots again.

All you need to do is make the solution by dissolving the concentrate in water and spray it over the weeds through the wand provided within the package.

In case of a broadcast application, attach the bottle with the garden hose and apply it all over the lawn surface. The 32 oz. concentrate will be enough to cover the 16000 sq.ft.

This miracle herbicide is safe to use on vast types of grasses including Bahiagrass, Fescues, Zoysia grass, Buffalograss, Bermudagrass, St. Augustine, Ryegrass, Centipedegrass, and Bluegrass.


  • Kills dandelions, clover and broadleaf weeds
  • Selective herbicide
  • Fast acting
  • Results in 6 hours
  • Safe for lawns
  • Can be applied to many type of grasses
  • Never harms the grass
  • Includes a wand for precise application

Methods to control weeds in Arizona

A lot of methods are used for controlling weeds in Arizona state. Some people go to get services from private companies but they are much more expensive. Here are some professional-grade methods for controlling weeds in Arizona. 

Most of the products are selective in nature that kills only the selective type of plants or weeds like only broadleaf or just narrow leaf. 

The other form of chemical products are non-selective that kills all the green plants on spraying.

But the desired results are only obtained if applied through the proper process. These are some methods of controlling weeds in Arizona state by using natural and chemical means.

1. Chemical weed sprays

Chemical sprays have priority among other methods due to their rapid results. Residues of the chemicals continue to work for eliminating the weeds for months.

But extra care is needed while using the chemicals on the landscape for weed control as they may harm the actual plants. 

  • Systemic weed treatments

Systemic chemicals are the proper and advanced chemical control of weeds as they attack just the actual plants to control. Using such chemicals keeps the land free of that selective weeds for some time, sometimes for a single season.

2. Natural and Organic Weed Control

Some people prefer to control the weeds with natural and organic means over the chemicals, due to the residual effects of chemicals. The natural and organic methods are also effective but are a bit slower than chemical methods.

  • Natural herbicides 

Natural herbicides are the best control method for post-emergents and show effective results on the annual weeds and grasses but have weak control over the perennials.

Common used natural herbicides are citrus oil that breaks down the waxy coating on leaves and makes them less holding for water. It ultimately leads them to death by dehydration.

Other effective natural herbicides are Acetic acid or Vinegar that has positive results in controlling certain weed species. I recommend the following product:

Calyptus 45% Pure Super Concentrated Vinegar | Dilutes to 9 Gallons | 9x Power Cleaning Vinegar |...
  • 9X STRONGER THAN VINEGAR: Highly concentrated and powerful. Calyptus...
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3. Soil Treatments

The soil treatment method is an effective method to control soil-specific weeds. As the pigweed loves to grow in sandy soils and simply altering the soil chemistry will give positive results in controlling such weeds.

Most common soil treatments are done by changing the soil pH to alkalinity.

How to Kill Weeds in Arizona

To keep your lawn and landscape free of weeds, you must have a proper and scheduled maintenance scheme. It keeps the actual plants growing fully. These are some daily routine techniques to kill weeds in Arizona.

1. Routine weed control

Take a routine notice of your landscape if any weeds are growing then do the immediate control before their establishment.

2. Killing of weeds

If you find a huge number of weeds growing all over the landscape, then go for the post-emergent selective chemical control method. Choose the narrow or broadleaf herbicides after properly examining the weed species.

3. Control future weeds

Using pre-emergent herbicides kills the weed seeds before their germination and keeps the lawn or landscape free of weeds in the future. 

Final Verdict

Selecting the right weed killer for any grass is never easy for any person with no guidance. Some common weeds can be killed by any herbicides but the tough weeds can only be controlled by proper herbicides.

Arizona regions have tough grasses and weeds in lawns and landscapes that are very difficult to control with local herbicides. A highly concentrated formula like Roundup QuikPro can do the right job in Arizona regions.

But the only problem growers face in weed control is finding the best weed killer for Arizona regions. I hope this guide really helps you in choosing the top weed killer for Arizona weeds.

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